fda-animal-health-kg

FDA Animal Health Knowledge Graph

FDA Center for Veterinary Medicine adverse event reports for animal drugs and devices as RDF, with the animal, the drugs and active ingredients, doses, routes and outcomes for 1.38 million reports, plus the approved animal drug applications of Animal Drugs @ FDA (the Green Book).

Overview Endpoints

The FDA Animal Health Knowledge Graph publishes the Center for Veterinary Medicine's adverse event reports and its approved animal drug applications as linked data: 1,378,854 reports from 1987 to 2026 and the Animal Drugs @ FDA (Green Book) application records, 148.2 million triples. Every source field is kept, and every record carries its source dataset, record ID, source URL and download date.

Adverse events. fdavet:AnimalEvent, IRI https://bmedesign.org/fda-animal-health-kg/id/animal-event/<unique AER id> (for example .../animal-event/usa_usfdacvm_2015_us_048928). Properties include fdavet:originalReceiveDate and fdavet:onsetDate (xsd:date), fdavet:numberOfAnimalsAffected, fdavet:numberOfAnimalsTreated, fdavet:primaryReporter, fdavet:typeOfInformation, fdavet:healthAssessmentPriorToExposure and fdavet:foreignOrDomestic.

Child nodes under each report: fdavet:AnimalEventAnimal (species, breed, gender, age with unit, weight with unit, reproductive status), one fdavet:AnimalEventDrug per drug (brand name, dosage form, route, ATC vet code, manufacturer name and CVM registration number, lot numbers, dose and frequency, use according to label, previous exposure) with fdavet:AnimalEventActiveIngredients children (ingredient name and dose), fdavet:AnimalEventOutcome (medical status and number of animals), fdavet:AnimalEventReceiver (the receiving FDA office) and fdavet:AnimalEventReaction (VeDDRA version, term code and term name).

Approved animal drugs. fdavet:AnimalDrugApplication, IRI .../animal-drug-application/<NADA or ANADA number>, from Animal Drugs @ FDA: sponsor, proprietary and established names, dosage form, route, species, approval and action dates, and the application's status history.

Responsible use. These are passive surveillance reports: counts are not incidence rates, and a report does not establish that a drug caused the event.

Source and license. openFDA animalandveterinary/event and Animal Drugs @ FDA: public domain U.S. government works. Reactions are coded in VeDDRA, maintained by the European Medicines Agency (EMA). VeDDRA term names are kept in the published graph with EMA acknowledged as their source, as EMA's legal notice permits; they are not covered by the CC0 dedication. Funded under NSF award 2535091 (Proto-OKN Theme 2: OKN-Fabric) through subaward 5136002. The graph is released under CC0 1.0.

provenance:
  - derivedFrom:
      label: openFDA animalandveterinary/event
      uri: https://open.fda.gov/apis/animalandveterinary/event/
      kind: Database
      license:
        data:
          label: Public Domain
          spdx: CC0-1.0
          uri: https://open.fda.gov/license/
  - derivedFrom:
      label: Animal Drugs @ FDA (Green Book)
      uri: https://animaldrugsatfda.fda.gov/
      kind: Database
      license:
        data:
          label: Public Domain
          spdx: CC0-1.0
  - derivedFrom:
      label: VeDDRA (Veterinary Dictionary for Drug Regulatory Activities), European Medicines Agency
      uri: https://www.ema.europa.eu/en/veterinary-regulatory-overview/post-authorisation-veterinary-medicines
      kind: Terminology
      license:
        data:
          label: EMA legal notice (reuse with acknowledgement of EMA as the source)
          uri: https://www.ema.europa.eu/en/about-us/about-website/legal-notice